XIAP anticorps (C-Term)
Aperçu rapide pour XIAP anticorps (C-Term) (ABIN2854771)
Antigène
Voir toutes XIAP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Réactivité croisée
- Humain, Souris
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Attributs du produit
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Rabbit Polyclonal antibody to XIAP (X-linked inhibitor of apoptosis)
XIAP antibody [C1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the C-terminus region of human XIAP. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HeLa , 293T , A431 , H1299 , NIH-3T3
Validation: KO/KD
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.78 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
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Autre désignation
- X-linked inhibitor of apoptosis
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Sujet
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The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
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Poids moléculaire
- 57 kDa
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ID gène
- 331
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UniProt
- P98170
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
Antigène
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