MTDH anticorps

N° du produit ABIN2854801

Cet anticorps Lapin Polyclonal détecte spécifiquement MTDH dans WB, IF, IHC (p) et ICC. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour MTDH anticorps (ABIN2854801)

Antigène: MTDH (Metadherin (MTDH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTDH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-MTDH anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit polyclonal antibody to LYRIC (metadherin)
LYRIC antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human LYRIC . The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: rat brain

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-MTDH (ABIN2854801)

Lai, Chuang, Liu, Ho, Lin, Anderson, Yeh: "Antibodies Against Modified NS1 Wing Domain Peptide Protect Against Dengue Virus Infection." dans: Scientific reports, Vol. 7, Issue 1, pp. 6975, (2019) (PubMed).

Détails sur MTDH

Antigène: MTDH (Metadherin (MTDH))

Autre désignation: metadherin

Sujet: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass membrane protein , Nucleus membrane, Single-pass membrane protein (By similarity) , Cell junction , tight junction (By similarity) , Nucleus , nucleolus (By similarity) , Cytoplasm , perinuclear region

Poids moléculaire: 64 kDa

ID gène: 92140

UniProt: Q86UE4

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization