CEBPB anticorps (N-Term)
Aperçu rapide pour CEBPB anticorps (N-Term) (ABIN2854833)
Antigène
Voir toutes CEBPB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- N-Term
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to C/EBP beta (CCAAT/enhancer binding protein (C/EBP), beta)
C/EBP beta antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human C/EBP beta. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Validatio: KO/KD, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.89 mg/mL
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Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
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Autre désignation
- CCAAT enhancer binding protein beta
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Sujet
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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Cellular Localization: Nucleus -
Poids moléculaire
- 36 kDa
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ID gène
- 1051
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UniProt
- P17676
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Pathways
- Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation
Antigène
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