MUC4 anticorps
Aperçu rapide pour MUC4 anticorps (ABIN2854862)
Antigène
Voir toutes MUC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit polyclonal antibody to Mucin 4 (mucin 4, cell surface associated)
Mucin 4 antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Mucin 4. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MUC4 (Mucin 4, Cell Surface Associated (MUC4))
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Autre désignation
- mucin 4, cell surface associated
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Sujet
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The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.
Cellular Localization: Membrane, Single-pass membrane protein (Potential) , Secreted -
Poids moléculaire
- 232 kDa
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ID gène
- 4585
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UniProt
- Q99102
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Pathways
- Regulation of Leukocyte Mediated Immunity
Antigène
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