MAPT anticorps
Aperçu rapide pour MAPT anticorps (ABIN2854882)
Antigène
Voir toutes MAPT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
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Rabbit Polyclonal antibody to Tau (microtubule-associated protein tau)
Tau antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Tau. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: IMR32 , SK-N-AS , mouse brain , SK-N-SH
Validation: Comparison, KO/KD, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.34 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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Autre désignation
- microtubule associated protein tau
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Sujet
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This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Cellular Localization: Cytoplasm , cytosol , Cell membrane, Peripheral membrane protein, Cytoplasmic side , cytoskeleton , Cell projection , axon -
Poids moléculaire
- 79 kDa
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ID gène
- 4137
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UniProt
- P10636
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Pathways
- Signalisation MAPK, Dynamique des Microtubules, M Phase, Regulation of Cell Size
Antigène
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