ACE2 anticorps (N-Term)

N° du produit ABIN2855030

L’anticorps Lapin Polyclonal anti-ACE2 a été validé pour WB, ELISA, ICC, FACS, IHC (p) et IF. Il convient pour détecter ACE2 dans des échantillons de Humain.

Aperçu rapide pour ACE2 anticorps (N-Term) (ABIN2855030)

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACE2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Classe de qualité: KO Validated

Détail du produit anti-ACE2 anticorps

Épitope: N-Term

Réactivité croisée: Green Monkey, Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)
ACE2 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human ACE2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ACE2

Antigène: ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Autre désignation: angiotensin I converting enzyme 2

Sujet: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Cellular Localization: Processed angiotensin-converting enzyme 2: Secreted , Cell membrane

Poids moléculaire: 92 kDa

ID gène: 59272

UniProt: Q9BYF1

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour