ADAM15 anticorps (N-Term)
Aperçu rapide pour ADAM15 anticorps (N-Term) (ABIN2855098)
Antigène
Voir toutes ADAM15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
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Rabbit Polyclonal antibody to ADAM15 (ADAM metallopeptidase domain 15)
ADAM15 antibody [N1N2], N-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human ADAM15. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HepG2 , NIH-3T3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.347 mg/mL
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Buffer
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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Autre désignation
- ADAM metallopeptidase domain 15
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Sujet
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The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Cellular Localization: Membrane -
Poids moléculaire
- 93 kDa
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ID gène
- 8751
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UniProt
- Q13444
Antigène
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