ADAR anticorps

N° du produit ABIN2855100

Cet anticorps anti-ADAR est un anticorps Lapin Polyclonal détectant ADAR dans WB, IF, IP, IHC (p) et ICC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour ADAR anticorps (ABIN2855100)

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Classe de qualité: KO Validated

Détail du produit anti-ADAR anticorps

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit Polyclonal antibody to ADAR1 (adenosine deaminase, RNA-specific)
ADAR1 antibody [N3C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ADAR1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-ADAR (ABIN2855100)

Stejskal, Rájecká, Covelo-Molares, Sinigaglia, Brožinová, Kašiarová, Dohnálková, Reyes-Gutierrez, Cahová, Keegan, O'Connell, Vaňáčová: "Global analysis by LC-MS/MS of N6-methyladenosine and inosine in mRNA reveal complex incidence." dans: RNA (New York, N.Y.), Vol. 31, Issue 4, pp. 514-528, (2025) (PubMed).

Détails sur ADAR

Antigène: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Autre désignation: adenosine deaminase RNA specific

Sujet: This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Cellular Localization: Cytoplasm , Nucleus , nucleolus

Poids moléculaire: 136 kDa

ID gène: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus