OTUB1 anticorps (Center)
Aperçu rapide pour OTUB1 anticorps (Center) (ABIN2855245)
Antigène
Voir toutes OTUB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Rat (Rattus), Porc, Boeuf (Vache)
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Réactivité croisée (Details)
- Rat (100 %), Pig (100 %), Bovine (100 %)
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Attributs du produit
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Rabbit Polyclonal antibody to OTUB1 (OTU domain, ubiquitin aldehyde binding 1)
OTUB1 antibody [N1C1] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human OTUB1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.249 mg/mL
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Buffer
- 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Autre désignation
- OTUB1
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Sujet
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 31 kDa
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ID gène
- 55611
Antigène
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