NXF1 anticorps (N-Term)

N° du produit ABIN2855280

Cet anticorps anti-NXF1 est un anticorps Lapin Polyclonal détectant NXF1 dans WB, IF, ICC et IHC (p). Adapté pour Humain.

Aperçu rapide pour NXF1 anticorps (N-Term) (ABIN2855280)

Antigène: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NXF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NXF1 anticorps

Épitope: N-Term

Séquence: CSSGALDYDI PTTASENLYF Q

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to TAP (nuclear RNA export factor 1)
TAP antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human TAP. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLa , Molt-4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur NXF1

Antigène: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Autre désignation: nuclear RNA export factor 1

Sujet: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.

Cellular Localization: Nucleus , nucleoplasm , Nucleus speckle , Cytoplasm

Poids moléculaire: 70 kDa

ID gène: 10482

UniProt: Q9UBU9