TLN1 anticorps (C-Term)

N° du produit ABIN2855327

L’anticorps Lapin Polyclonal anti-TLN1 a été validé pour WB et IHC (p). Il convient pour détecter TLN1 dans des échantillons de Humain.

Aperçu rapide pour TLN1 anticorps (C-Term) (ABIN2855327)

Antigène: TLN1 (Talin 1 (TLN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TLN1 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to Talin-1 (talin 1)
Talin-1 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human Talin-1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Neuro2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.09 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TLN1

Antigène: TLN1 (Talin 1 (TLN1))

Autre désignation: talin 1

Sujet: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Cellular Localization: Cell projection , ruffle membrane, Peripheral membrane protein, Cytoplasmic side (By similarity) , Cytoplasm , cytoskeleton (By similarity)

Poids moléculaire: 270 kDa

ID gène: 7094

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location