Caldesmon anticorps (N-Term)
Aperçu rapide pour Caldesmon anticorps (N-Term) (ABIN2855409)
Antigène
Voir toutes Caldesmon (CALD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to Caldesmon (caldesmon 1)
Caldesmon antibody [N1N2], N-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human Caldesmon. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: 293T, A431
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.86 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Autre désignation
- caldesmon 1
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Sujet
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This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
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Poids moléculaire
- 93 kDa
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ID gène
- 800
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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