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Caldesmon anticorps (pSer789)

CALD1 Reactivité: Humain, Rat, Souris WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6255507
  • Antigène Voir toutes Caldesmon (CALD1) Anticorps
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Épitope
    • 25
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer789
    Reactivité
    • 84
    • 81
    • 62
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 100
    • 19
    Lapin
    Clonalité
    • 83
    • 36
    Polyclonal
    Conjugué
    • 73
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Caldesmon est non-conjugé
    Application
    • 72
    • 31
    • 30
    • 27
    • 26
    • 19
    • 17
    • 16
    • 11
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Phospho-Caldesmon (Ser789) Antibody detects endogenous levels of Caldesmon only when phosphorylated at Serine 789.
    Homologie
    Pig,Horse,Sheep,Rabbit,Dog
    Purification
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogène
    A synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789.
    Isotype
    IgG
    Top Product
    Discover our top product CALD1 Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Autre désignation
    CALD1 (CALD1 Produits)
    Synonymes
    anticorps CDM, anticorps H-CAD, anticorps HCAD, anticorps L-CAD, anticorps LCAD, anticorps NAG22, anticorps l-Cad, anticorps 4833423D12Rik, anticorps AI195384, anticorps AV071549, anticorps AW536160, anticorps C920027I18Rik, anticorps CALD1, anticorps Caldesmon, anticorps caldesmon 1, anticorps CALD1, anticorps Cald1
    Sujet

    Description: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).

    Gene: CALD1

    Poids moléculaire
    80kDa
    ID gène
    800
    UniProt
    Q05682
    Pathways
    Myometrial Relaxation and Contraction
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