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LIG3 anticorps

KO Validated LIG3 Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855567
  • Antigène Voir toutes LIG3 Anticorps
    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
    Reactivité
    • 48
    • 16
    • 16
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 3
    Lapin
    Clonalité
    • 46
    • 2
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIG3 est non-conjugé
    Application
    • 34
    • 20
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Rabbit Polyclonal antibody to DNA ligase III (ligase III, DNA, ATP-dependent)
    DNA ligase III antibody
    Purification
    Purified by antigen-affinity chromatography.
    Classe de qualité
    KO Validated
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human DNA ligase III. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product LIG3 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: KO/KD, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.81 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
    Autre désignation
    DNA ligase 3 (LIG3 Produits)
    Synonymes
    anticorps orf36, anticorps DDBDRAFT_0218523, anticorps DDBDRAFT_0232266, anticorps DDB_0218523, anticorps DDB_0232266, anticorps LIG3, anticorps wu:fb12c02, anticorps wu:fd10b03, anticorps wu:fm79b09, anticorps LIG2, anticorps D11Wsu78e, anticorps An02g06890, anticorps AO090003000668, anticorps lig3, anticorps DNA ligase III, anticorps BRCT domain-containing protein, anticorps DNA ligase 3, anticorps ligase III, DNA, ATP-dependent, anticorps ligase III, DNA, ATP-dependent L homeolog, anticorps orf36, anticorps lig3, anticorps LIG3, anticorps Lig3, anticorps Bm1_22840, anticorps ANI_1_2644024, anticorps AOR_1_1174154, anticorps LOC100634887, anticorps lig3.L
    Sujet
    This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Cellular Localization: Nucleus
    Poids moléculaire
    113 kDa
    ID gène
    3980
    UniProt
    P49916
    Pathways
    Réparation de l'ADN
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