KLF5 anticorps

N° du produit ABIN2855604

Détail du produit anti-KLF5 anticorps

Antigène: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF5 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Rabbit Polyclonal antibody to KLF5 (Kruppel-like factor 5 (intestinal))
KLF5 antibody

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human KLF5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: KLF5-transfected 293T , HeLa (500 μM CoCl2 treatment for 24 hr and 10 μM MG132 treatment for 2 hr)

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-KLF5 (ABIN2855604)

Sun, Li, Wang, Yue, Bai, Bian, Hao, Sun, Zhang, Liu: "Increased AT2R expression is induced by AT1R autoantibody via two axes, Klf-5/IRF-1 and circErbB4/miR-29a-5p, to promote VSMC migration." dans: Cell death & disease, Vol. 11, Issue 6, pp. 432, (2020) (PubMed).

Ma, Chang, Zhao, Zhao, Xiong, Cao, Yuan, Zhang, Wang, Geng, Zheng, Li: "KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression." dans: Scientific reports, Vol. 7, Issue 1, pp. 15683, (2019) (PubMed).

Détails sur KLF5

Antigène: KLF5 (Kruppel-Like Factor 5 (Intestinal) (KLF5))

Autre désignation: Kruppel like factor 5 (KLF5 Produits)

Synonymes: anticorps KLF5, anticorps klf5, anticorps MGC115081, anticorps BTEB2, anticorps Bteb2, anticorps IKLF, anticorps bteb2, anticorps 4930520J07Rik, anticorps CKLF, anticorps Kruppel like factor 5, anticorps Kruppel-like factor 5 (intestinal) S homeolog, anticorps Kruppel-like factor 5, anticorps KLF5, anticorps klf5.S, anticorps Klf5

Sujet: This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Cellular Localization: Nucleus

Poids moléculaire: 51 kDa

ID gène: 688

UniProt: Q13887