SART1 anticorps (Internal Region)

N° du produit ABIN2855616

Détail du produit anti-SART1 anticorps

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SART1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Attributs du produit: Rabbit Polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
SART1 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human SART1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Commentaires:

Conjugation Note: MH

Positive Control: Jurkat , Raji , K562 , THP-1 , HL-60 , NCI-H929 , NIH-3T3 , JC , BCL-1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.76 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur SART1

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Autre désignation: SART1 (SART1 Produits)

Synonymes: anticorps Dmel\\CG6686, anticorps SART1, anticorps MGC53679, anticorps MGC132129, anticorps zgc:91927, anticorps Ara1, anticorps HOMS1, anticorps SART1259, anticorps SNRNP110, anticorps Snu66, anticorps U5-110K, anticorps CG6686 gene product from transcript CG6686-RB, anticorps SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog, anticorps SART1, U4/U6.U5 tri-snRNP-associated protein 1, anticorps squamous-cell carcinoma T-cell-recognized antigen, anticorps squamous cell carcinoma antigen recognized by T cells 1, anticorps CG6686, anticorps sart1.S, anticorps sart1, anticorps SART1, anticorps Sart1

Sujet: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Cellular Localization: Nucleus

Poids moléculaire: 90 kDa

ID gène: 9092

Pathways: Ribonucleoprotein Complex Subunit Organization