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SART1 anticorps (C-Term)

SART1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856790
  • Antigène Voir toutes SART1 Anticorps
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Épitope
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 32
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 2
    • 1
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SART1 est non-conjugé
    Application
    • 30
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris, Rat (Rattus), Xenopus laevis, Poisson zèbre (Danio rerio), Boeuf (Vache)
    Réactivité croisée (Details)
    Mouse (99 %), Rat (99 %), Xenopus laevis (89 %), Zebrafish (81 %), Bovine (99 %)
    Attributs du produit
    Rabbit polyclonal antibody to SART1 (squamous cell carcinoma antigen recognized by T cells)
    SART1 antibody [C1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the C-terminus region of human SART1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product SART1 Anticorps primaire
  • Indications d'application
    Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
    Commentaires

    Positive Control: H1299 , HeLa , HepG2 , Molt-4 , Raji

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))
    Autre désignation
    SART1 (SART1 Produits)
    Synonymes
    anticorps Dmel\\CG6686, anticorps SART1, anticorps MGC53679, anticorps MGC132129, anticorps zgc:91927, anticorps Ara1, anticorps HOMS1, anticorps SART1259, anticorps SNRNP110, anticorps Snu66, anticorps U5-110K, anticorps CG6686 gene product from transcript CG6686-RB, anticorps SART1, U4/U6.U5 tri-snRNP-associated protein 1 S homeolog, anticorps SART1, U4/U6.U5 tri-snRNP-associated protein 1, anticorps squamous-cell carcinoma T-cell-recognized antigen, anticorps squamous cell carcinoma antigen recognized by T cells 1, anticorps CG6686, anticorps sart1.S, anticorps sart1, anticorps SART1, anticorps Sart1
    Sujet
    This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

    Cellular Localization: Nucleus
    Poids moléculaire
    90 kDa
    ID gène
    9092
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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