EIF4E2 anticorps

N° du produit ABIN2855740

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF4E2 dans WB et IP. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour EIF4E2 anticorps (ABIN2855740)

Antigène: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4E2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Classe de qualité: KO Validated

Détail du produit anti-EIF4E2 anticorps

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit polyclonal antibody to EIF4EL3 (eukaryotic translation initiation factor 4E family member 2)
EIF4E2 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human EIF4E2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.27 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-EIF4E2 (ABIN2855740)

Juszkiewicz, Slodkowicz, Lin, Freire-Pritchett, Peak-Chew, Hegde: "Ribosome collisions trigger cis-acting feedback inhibition of translation initiation." dans: eLife, Vol. 9, (2020) (PubMed).

Garzia, Jafarnejad, Meyer, Chapat, Gogakos, Morozov, Amiri, Shapiro, Molina, Tuschl, Sonenberg: "The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs." dans: Nature communications, Vol. 8, pp. 16056, (2018) (PubMed).

Détails sur EIF4E2

Antigène: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Autre désignation: eukaryotic translation initiation factor 4E family member 2

Sujet: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Poids moléculaire: 28 kDa

ID gène: 9470

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interactome