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SOCS5 anticorps (N-Term)

SOCS5 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2855921
  • Antigène Voir toutes SOCS5 Anticorps
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    Épitope
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 29
    • 3
    • 2
    Humain, Souris
    Hôte
    • 25
    • 3
    • 1
    Lapin
    Clonalité
    • 28
    • 1
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SOCS5 est non-conjugé
    Application
    • 26
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Rat (Rattus), Porc, Poulet, Macaque rhésus, Boeuf (Vache)
    Réactivité croisée (Details)
    Rat (100 %), Pig (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)
    Attributs du produit
    Rabbit Polyclonal antibody to SOCS5 (suppressor of cytokine signaling 5)
    SOCS5 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOCS5. The exact sequence is proprietary.
    Isotype
    IgG
  • Indications d'application
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Commentaires

    Positive Control: Molt-4 , NT2D1 , PC-3 , mouse testis

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Cui, Chen, Zhang, Cheng, Pan, Huang, Hu, Zhang, Wang, Zhu, Chen, Liu, Zhao, Wu, Yang, Liu, Zhang, Yu, Yin, Jing, Rehman, Tian, Pan, Jia: "Duck Tembusu Virus Utilizes miR-221-3p Expression to Facilitate Viral Replication via Targeting of Suppressor of Cytokine Signaling 5." dans: Frontiers in microbiology, Vol. 11, pp. 596, (2020) (PubMed).

    Tsai, Kuo, Hung, Wu, Wu, Chang, Kuo, Hsu: "Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy." dans: Molecular therapy. Nucleic acids, Vol. 13, pp. 543-555, (2018) (PubMed).

  • Antigène
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    Autre désignation
    SOCS5 (SOCS5 Produits)
    Synonymes
    anticorps SOCS5, anticorps cis6, anticorps cish5, anticorps cish6, anticorps socs-5, anticorps GB18949, anticorps socs5, anticorps zgc:153506, anticorps CIS6, anticorps CISH6, anticorps Cish5, anticorps SOCS-5, anticorps 1810018L08Rik, anticorps mKIAA0671, anticorps RGD1564914, anticorps suppressor of cytokine signaling 5, anticorps suppressor of cytokine signaling 5a, anticorps suppressor of cytokine signaling 5 L homeolog, anticorps SOCS5, anticorps socs5, anticorps LOC552036, anticorps socs5a, anticorps Tsp_07018, anticorps socs5.L, anticorps Socs5
    Sujet
    The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

    Poids moléculaire
    61 kDa
    ID gène
    9655
    Pathways
    Signalistation JAK/STAT, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
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