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ADAM10 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement ADAM10 dans WB, ICC, IF et IHC (p). Il présente une réactivité envers Humain.
N° du produit ABIN2855998

Aperçu rapide pour ADAM10 anticorps (ABIN2855998)

Antigène

Voir toutes ADAM10 Anticorps
ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivité

  • 76
  • 32
  • 31
  • 2
  • 1
  • 1
Humain

Hôte

  • 62
  • 20
  • 2
  • 1
Lapin

Clonalité

  • 54
  • 31
Polyclonal

Conjugué

  • 43
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ADAM10 est non-conjugé

Application

  • 53
  • 21
  • 21
  • 18
  • 15
  • 13
  • 13
  • 11
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  •  Réactivité croisée

    Drosophila melanogaster, Humain, Souris

    Attributs du produit

    Rabbit Polyclonal antibody to ADAM10 (disintegrin and metalloproteinase domain-containing protein 10)
    ADAM10 antibody [N2C1], Internal

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: THP-1

    Validation: Orthogonal

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.48 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

    Autre désignation

    ADAM metallopeptidase domain 10

    Sujet

    Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

    Cellular Localization: Cell membrane , Endomembrane system

    Poids moléculaire

    84 kDa

    ID gène

    102

    UniProt

    O14672

    Pathways

    Signalisation Notch, EGFR Signaling Pathway
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