RFC2 anticorps
Aperçu rapide pour RFC2 anticorps (ABIN2856035)
Antigène
Voir toutes RFC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to RFC2 (replication factor C (activator 1) 2, 40 kDa)
RFC2 antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human RFC2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: H1299 , 293T , A431 , HeLa , HepG2
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.43 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))
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Autre désignation
- replication factor C subunit 2
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Sujet
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The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Cellular Localization: Nucleus -
Poids moléculaire
- 39 kDa
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ID gène
- 5982
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UniProt
- P35250
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Pathways
- Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA
Antigène
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