RNASE1 anticorps (Center)
Aperçu rapide pour RNASE1 anticorps (Center) (ABIN2856141)
Antigène
Voir toutes RNASE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Attributs du produit
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Rabbit Polyclonal antibody to Ribonuclease A (ribonuclease, RNase A family, 1 (pancreatic))
Ribonuclease A antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Ribonuclease A. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Commentaires
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Positive Control: U87-MG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))
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Autre désignation
- Ribonuclease A
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Sujet
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This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Cellular Localization: Secreted -
Poids moléculaire
- 18 kDa
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ID gène
- 6035
Antigène
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