RNASE1 anticorps (N-Term)

N° du produit ABIN1881752

Détail du produit anti-RNASE1 anticorps

Antigène: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Épitope: AA 14-42, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNASE1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RNASE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RNASE1.

Clone: RB42410

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-RNASE1 (ABIN1881752)

DAlessio: "It takes two to flirt with a dimeric RNase." dans: Biopolymers, Vol. 91, Issue 12, pp. 989-94, (2009) (PubMed).

Kövér, Bruix, Santoro, Batta, Laurents, Rico: "The solution structure and dynamics of human pancreatic ribonuclease determined by NMR spectroscopy provide insight into its remarkable biological activities and inhibition." dans: Journal of molecular biology, Vol. 379, Issue 5, pp. 953-65, (2008) (PubMed).

Cybulski, Wokołorczyk, Jakubowska, Gliniewicz, Sikorski, Huzarski, Debniak, Narod, Lubiński: "DNA variation in MSR1, RNASEL and E-cadherin genes and prostate cancer in Poland." dans: Urologia internationalis, Vol. 79, Issue 1, pp. 44-9, (2007) (PubMed).

Détails sur RNASE1

Antigène: RNASE1 (Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1))

Autre désignation: RNASE1 (RNASE1 Produits)

Synonymes: anticorps RNASE1, anticorps RNS1, anticorps ATRNS1, anticorps RIBONUCLEASE 1, anticorps T17M13.16, anticorps T17M13_16, anticorps ribonuclease 1, anticorps RIB1, anticorps AI574248, anticorps Rib-1, anticorps Rib1, anticorps SRN, anticorps ribonuclease A family member 1, pancreatic, anticorps ribonuclease pancreatic-like, anticorps ribonuclease A family member k6, anticorps Ribonuclease 1, anticorps ribonuclease 1, anticorps ribonuclease, RNase A family, 1 (pancreatic), anticorps ribonuclease pancreatic, anticorps RNASE1, anticorps LOC475395, anticorps RNASE6, anticorps Rnase1, anticorps RNS1, anticorps LOC101113761

Sujet: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq].

Poids moléculaire: 17644

NCBI Accession: NP_002924, NP_937875, NP_937877, NP_937878

UniProt: P07998