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Cytokeratin 18 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Cytokeratin 18 dans WB, IF, IHC (p), IP et ICC. Il présente une réactivité envers Humain.
N° du produit ABIN2856142

Aperçu rapide pour Cytokeratin 18 anticorps (ABIN2856142)

Antigène

Voir toutes Cytokeratin 18 (KRT18) Anticorps
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivité

  • 294
  • 152
  • 127
  • 75
  • 65
  • 57
  • 53
  • 49
  • 39
  • 38
  • 34
  • 34
  • 34
  • 18
  • 9
  • 9
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
Humain

Hôte

  • 173
  • 160
  • 3
  • 1
  • 1
  • 1
Lapin

Clonalité

  • 198
  • 138
  • 3
Polyclonal

Conjugué

  • 169
  • 30
  • 22
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Cet anticorp Cytokeratin 18 est non-conjugé

Application

  • 278
  • 165
  • 103
  • 102
  • 74
  • 57
  • 54
  • 53
  • 47
  • 40
  • 34
  • 31
  • 13
  • 8
  • 8
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Classe de qualité

KO Validated
  •  Réactivité croisée

    Chien, Humain, Souris

    Attributs du produit

    Rabbit polyclonal antibody to Cytokeratin 18 (keratin 18)
    Cytokeratin 18 antibody [N2C2], Internal

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human Cytokeratin 18. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: H1299 , HepG2 , HeLa

    Validation: KO/KD

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.54 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Autre désignation

    keratin 18

    Sujet

    KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

    Cellular Localization: Cytoplasm , perinuclear region

    Poids moléculaire

    48 kDa

    ID gène

    3875

    UniProt

    P05783

    Pathways

    Apoptose, Caspase Cascade in Apoptosis
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