Factor XI anticorps

N° du produit ABIN2856233

L’anticorps Lapin Polyclonal anti-Factor XI a été validé pour WB et IHC (p). Il convient pour détecter Factor XI dans des échantillons de Humain.

Aperçu rapide pour Factor XI anticorps (ABIN2856233)

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor XI est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Factor XI anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Factor XI (coagulation factor XI)
Factor XI antibody [N1N3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Factor XI. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.85 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Factor XI

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Autre désignation: coagulation factor XI

Sujet: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Cellular Localization: Secreted

Poids moléculaire: 70 kDa

ID gène: 2160

UniProt: P03951