GLRA1 anticorps

N° du produit ABIN2856259

Détail du produit anti-GLRA1 anticorps

Antigène: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLRA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Rat

Attributs du produit: Rabbit Polyclonal antibody to Glycine Receptor alpha1 (glycine receptor, alpha 1)
Glycine Receptor alpha1 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Glycine Receptor alpha 1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLaS3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.43 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur GLRA1

Antigène: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Autre désignation: glycine receptor alpha 1 (GLRA1 Produits)

Synonymes: anticorps GLYRA1, anticorps HKPX1, anticorps STHE, anticorps [a]Z1, anticorps B230397M16Rik, anticorps nmf11, anticorps oscillator, anticorps ot, anticorps spasmodic, anticorps spd, anticorps glycine receptor alpha 1, anticorps glycine receptor, alpha 1, anticorps glycine receptor, alpha 1 subunit, anticorps GLRA1, anticorps Glra1, anticorps glra1

Sujet: The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Cell membrane, Multi-pass membrane protein

Poids moléculaire: 53 kDa

ID gène: 2741

UniProt: P23415

Pathways: Synaptic Membrane