DPM1 anticorps (Center)
Aperçu rapide pour DPM1 anticorps (Center) (ABIN2856272)
Antigène
Voir toutes DPM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Souris, Boeuf (Vache), Porc, Rat (Rattus), Xenopus laevis
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Réactivité croisée (Details)
- Mouse (90 %), Bovine (92 %), Pig (93 %), Rat (91 %), Xenopus laevis (86 %)
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Attributs du produit
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Rabbit Polyclonal antibody to DPM1 (dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit)
DPM1 antibody [N1C2] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human DPM1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Commentaires
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Positive Control: NT2D1 , U87-MG , MCF-7
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.95 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DPM1 (Dolichyl-Phosphate Mannosyltransferase Polypeptide 1, Catalytic Subunit (DPM1))
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Autre désignation
- DPM1
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Sujet
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Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
Cellular Localization: Endoplasmic reticulum -
Poids moléculaire
- 30 kDa
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ID gène
- 8813
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Pathways
- Inositol Metabolic Process
Antigène
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