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CD2AP anticorps

Cd2ap Reactivité: Humain WB, ICC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856284
  • Antigène Voir toutes CD2AP (Cd2ap) Anticorps
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Reactivité
    • 22
    • 8
    • 6
    Humain
    Hôte
    • 22
    • 2
    • 1
    Lapin
    Clonalité
    • 23
    • 2
    Polyclonal
    Conjugué
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD2AP est non-conjugé
    Application
    • 13
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Rabbit Polyclonal antibody to CD2AP (CD2-associated protein)
    CD2AP antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Recombinant protein encompassing a sequence within the center region of human CD2AP. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product Cd2ap Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T , A375 , Rat2 , A431 , HeLa , HepG2 , K562 , THP-1 , HL-60

    Validation: Comparison, Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.17 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    Autre désignation
    CD2 associated protein (Cd2ap Produits)
    Synonymes
    anticorps cd2apl, anticorps fj51c01, anticorps im:7153970, anticorps si:ch211-207n9.1, anticorps wu:fj51c01, anticorps zgc:103705, anticorps DKFZp469E061, anticorps CMS, anticorps AL024079, anticorps C78928, anticorps METS-1, anticorps Mets1, anticorps CD2-associated protein L homeolog, anticorps CD2 associated protein, anticorps CD2-associated protein, anticorps cd2ap.L, anticorps CD2AP, anticorps cd2ap, anticorps Cd2ap
    Sujet
    This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , ruffle
    Poids moléculaire
    71 kDa
    ID gène
    23607
    UniProt
    Q9Y5K6
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