CD2AP anticorps (AA 320-400)

N° du produit ABIN7227732

L’anticorps anti-CD2AP Polyclonal Lapin est utilisé pour la détection de CD2AP dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CD2AP anticorps (AA 320-400) (ABIN7227732)

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD2AP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD2AP anticorps

Épitope: AA 320-400

Fonction: Rabbit Anti-CD2AP Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CD2AP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CD2AP protein at AA range: 320-400

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD2AP

Antigène: CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))

Autre désignation: CD2AP

Sujet: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domainsCD2AP (CD2 Associated Protein) encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of CD2AP is implicated in susceptibility to glomerular disease. CD2AP is a Protein Coding gene. Diseases associated with CD2AP include Glomerulosclerosis, Focal Segmental, 3 and Sporadic Idiopathic Steroid-Resistant Nephrotic Syndrome With Focal Segmental Hyalinosis.

Poids moléculaire: 70kD

ID gène: 23607

UniProt: Q9Y5K6