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MTA2 anticorps (C-Term)

MTA2 Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2856347
  • Antigène Voir toutes MTA2 Anticorps
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    Épitope
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 44
    • 32
    • 29
    • 10
    • 9
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    Humain
    Hôte
    • 43
    • 4
    Lapin
    Clonalité
    • 42
    • 5
    Polyclonal
    Conjugué
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MTA2 est non-conjugé
    Application
    • 47
    • 13
    • 10
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain
    Attributs du produit
    Rabbit polyclonal antibody to MTA2 (metastasis associated 1 family, member 2)
    MTA2 antibody [C3], C-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogène
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MTA2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product MTA2 Anticorps primaire
  • Indications d'application
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Commentaires

    Positive Control: 293T, A431

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.67 mg/mL
    Buffer
    1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Agent conservateur
    Thimerosal (Merthiolate)
    Précaution d'utilisation
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    Autre désignation
    metastasis associated 1 family member 2 (MTA2 Produits)
    Synonymes
    anticorps MTA1L1, anticorps PID, anticorps fd61b05, anticorps wu:fd61b05, anticorps wu:fi29g02, anticorps zgc:63487, anticorps pid, anticorps mta1l1, anticorps MTA2, anticorps DKFZp470E0911, anticorps AW550797, anticorps Mata1l1, anticorps Mta1l1, anticorps mmta2, anticorps metastasis associated 1 family member 2, anticorps metastasis associated 1 family, member 2, anticorps metastasis-associated gene family, member 2, anticorps metastasis associated 1 family member 2 L homeolog, anticorps MTA2, anticorps mta2, anticorps Mta2, anticorps mta2.L
    Sujet
    This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.

    Cellular Localization: Nucleus
    Poids moléculaire
    75 kDa
    ID gène
    9219
    UniProt
    O94776
    Pathways
    Chromatin Binding
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