MTA2 anticorps (C-Term)

N° du produit ABIN390610

Détail du produit anti-MTA2 anticorps

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Épitope: AA 516-544, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PID/MTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-544 amino acids from the C-terminal region of human PID/MTA2.

Clone: RB20031

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MTA2

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Autre désignation: PID/MTA2 (MTA2 Produits)

Synonymes: anticorps MTA1L1, anticorps PID, anticorps fd61b05, anticorps wu:fd61b05, anticorps wu:fi29g02, anticorps zgc:63487, anticorps pid, anticorps mta1l1, anticorps MTA2, anticorps DKFZp470E0911, anticorps AW550797, anticorps Mata1l1, anticorps Mta1l1, anticorps mmta2, anticorps metastasis associated 1 family member 2, anticorps metastasis associated 1 family, member 2, anticorps metastasis-associated gene family, member 2, anticorps metastasis associated 1 family member 2 L homeolog, anticorps MTA2, anticorps mta2, anticorps Mta2, anticorps mta2.L

Sujet: MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small family of different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.

Poids moléculaire: 75023

ID gène: 9219

NCBI Accession: NP_004730

UniProt: O94776

Pathways: Chromatin Binding