AKAP10 anticorps (C-Term)

N° du produit ABIN2856375

Détail du produit anti-AKAP10 anticorps

Antigène: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP10 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Mouse (85 %), Rat (85 %)

Attributs du produit: Rabbit Polyclonal antibody to AKAP10 (A kinase (PRKA) anchor protein 10)
AKAP10 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP10. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Commentaires:

Positive Control: Synthetic peptide: 1:8,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur AKAP10

Antigène: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Autre désignation: AKAP10 (AKAP10 Produits)

Synonymes: anticorps MGC84612, anticorps AKAP10, anticorps fc10g11, anticorps wu:fc10g11, anticorps si:dkey-197m14.4, anticorps AKAP-10, anticorps D-AKAP-2, anticorps D-AKAP2, anticorps PRKA10, anticorps 1500031L16Rik, anticorps B130049N18Rik, anticorps D-akap2, anticorps Akap10, anticorps A-kinase anchoring protein 10, anticorps A-kinase anchoring protein 10 L homeolog, anticorps A kinase (PRKA) anchor protein 10, anticorps AKAP10, anticorps akap10.L, anticorps akap10, anticorps Akap10

Sujet: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.

Cellular Localization: Mitochondrion , Membrane , Cytoplasm

Poids moléculaire: 74 kDa

ID gène: 11216

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling