PDGFRB anticorps
Aperçu rapide pour PDGFRB anticorps (ABIN285643)
Antigène
Voir toutes PDGFRB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody reacts with bovine albumin by immunoelectrophoresis and ELISA,and may also cross-react with albumin from other species.1 ml@ 1 mg/ml
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Purification
- Protein G affinity chromatography
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Immunogène
- PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen.
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Indications d'application
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Purified by protein G chromatography and supplied in PBS with 0.05 % NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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Autre désignation
- PDGFr
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Sujet
- Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Antigène
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