PDGFRB anticorps

N° du produit ABIN285643

Détail du produit anti-PDGFRB anticorps

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivité: Mammifères

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFRB est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This antibody reacts with bovine albumin by immunoelectrophoresis and ELISA,and may also cross-react with albumin from other species.1 ml@ 1 mg/ml

Purification: Protein G affinity chromatography

Immunogène: PDGFr antibody was raised in sheep using PDGFr-rDNA expression of the b domain (GST fusion) as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified by protein G chromatography and supplied in PBS with 0.05 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur PDGFRB

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: PDGFr (PDGFRB Produits)

Synonymes: anticorps AI528809, anticorps CD140b, anticorps PDGFR-1, anticorps Pdgfr, anticorps CD140B, anticorps IBGC4, anticorps JTK12, anticorps PDGFR, anticorps PDGFR1, anticorps platelet derived growth factor receptor, beta polypeptide, anticorps platelet derived growth factor receptor beta, anticorps Pdgfrb, anticorps PDGFRB

Sujet: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling