TEAD4 anticorps (Center)

N° du produit ABIN2856634

Cet anticorps Lapin Polyclonal détecte spécifiquement TEAD4 dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour TEAD4 anticorps (Center) (ABIN2856634)

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TEAD4 anticorps

Épitope: Center

Réactivité croisée: Souris, Porc

Réactivité croisée (Details): Mouse (91 %), Pig (94 %)

Attributs du produit: Rabbit Polyclonal antibody to TEAD4 (TEA domain family member 4)
TEAD4 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human TEAD4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: HepG2 necleus

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-TEAD4 (ABIN2856634)

Zhang, Li, Wu, Ge, Song, Wang, Yuan, Jiang, Wang, Cheng: "TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma." dans: Cancer cell international, Vol. 18, pp. 178, (2018) (PubMed).

Détails sur TEAD4

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Autre désignation: TEAD4

Sujet: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.

Cellular Localization: Nucleus

Poids moléculaire: 48 kDa

ID gène: 7004

Pathways: Regulation of Lipid Metabolism by PPARalpha