BAIAP2L1 anticorps
Aperçu rapide pour BAIAP2L1 anticorps (ABIN2856677)
Antigène
Voir toutes BAIAP2L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Attributs du produit
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Rabbit Polyclonal antibody to BAIAP2L1 (BAI1-associated protein 2-like 1)
BAIAP2L1 antibody [N1C1] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human BAIAP2L1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HeLa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.55 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin Interaction." dans: Frontiers in synaptic neuroscience, Vol. 10, pp. 27, (2018) (PubMed).
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: "Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin Interaction." dans: Frontiers in synaptic neuroscience, Vol. 10, pp. 27, (2018) (PubMed).
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- BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))
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Autre désignation
- BAI1 associated protein 2 like 1
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Sujet
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This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
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Poids moléculaire
- 57 kDa
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ID gène
- 55971
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UniProt
- Q9UHR4
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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