Fatty Acid Synthase anticorps (N-Term)
Aperçu rapide pour Fatty Acid Synthase anticorps (N-Term) (ABIN2856708)
Antigène
Voir toutes Fatty Acid Synthase (FASN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- N-Term
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
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Rabbit Polyclonal antibody to Fatty Acid Synthase (fatty acid synthase)
Fatty Acid Synthase antibody [N1], N-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Mouse brain , Molt-4 , PC-12 , Rat2 , 293T
Validation: KO/KD, Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Fatty Acid Synthase (FASN)
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Autre désignation
- fatty acid synthase
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Sujet
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The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Cellular Localization: Cytoplasm , Melanosome -
Poids moléculaire
- 273 kDa
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ID gène
- 2194
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UniProt
- P49327
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Pathways
- AMPK Signaling
Antigène
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