GLDC anticorps
Aperçu rapide pour GLDC anticorps (ABIN2856747)
Antigène
Voir toutes GLDC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
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Rabbit Polyclonal antibody to Glycine dehydrogenase (glycine dehydrogenase (decarboxylating))
Glycine dehydrogenase antibody [N3C2-2], Internal -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Glycine dehydrogenase. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HepG2
Validation: Comparison
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.46 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GLDC (Glycine Dehydrogenase (GLDC))
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Autre désignation
- glycine decarboxylase
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Sujet
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The enzyme system for cleavage of glycine (glycine cleavage system, GCS, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes, see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM]
Cellular Localization: Mitochondrion -
Poids moléculaire
- 113 kDa
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ID gène
- 2731
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UniProt
- P23378
Antigène
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