FBXL3 anticorps

N° du produit ABIN2856775

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXL3 dans WB, ICC et IF. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour FBXL3 anticorps (ABIN2856775)

Antigène: FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXL3 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-FBXL3 anticorps

Réactivité croisée: Humain, Souris

Attributs du produit: Rabbit Polyclonal antibody to FBXL3 (F-box and leucine-rich repeat protein 3)
FBXL3 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human FBXL3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: C2C12 , Molt-4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.41 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-FBXL3 (ABIN2856775)

Xu, Zhou, Yang, Chen, Li, Zhao, Liu, Li, Tan, Xiong, Sun: "The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor." dans: Nature communications, Vol. 8, pp. 14002, (2018) (PubMed).

Détails sur FBXL3

Antigène: FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

Autre désignation: F-box and leucine rich repeat protein 3

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.

Cellular Localization: Nucleus , Cytoplasm

Poids moléculaire: 49 kDa

ID gène: 26224

UniProt: Q9UKT7

Pathways: Photoperiodism