CAMK2D anticorps

N° du produit ABIN2856806

Détail du produit anti-CAMK2D anticorps

Antigène: CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2D est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Specificité: Cross-reactivity may occur with other CaM kinase II subunits.

Réactivité croisée: Humain, Souris, Lapin, Rat, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to CaMKII delta (calcium/calmodulin-dependent protein kinase II delta)
CaMKII delta antibody

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human CaMKII delta. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2 , mouse brain , rat brain

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.62 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CAMK2D (ABIN2856806)

Liu, Zhong, Zhou, Yang, Tan, Li, Gao, Sun, Li, Jin, Cao, Yuan, Liu, Liang, Li, Du, Zhao, Xue, Zhao, Song, Ling, Li: "Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." dans: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).

Li, Liu, Li, Zheng, Xu, Liu, Sun, Li, Ji, Liu, Zhang, Zhao, Du, Liu, Zhong, Sun, Wang, Song, Zhang, Qin, Ling, Wang, Li: "TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling." dans: Nature communications, Vol. 10, Issue 1, pp. 1589, (2019) (PubMed).

Xu, Wang, Zhang, Gong, Gutierrez Cortes, Zhu, Yoon, Tian, Wang: "CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation." dans: Nature communications, Vol. 7, pp. 13189, (2016) (PubMed).

Détails sur CAMK2D

Antigène: CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))

Autre désignation: calcium/calmodulin dependent protein kinase II delta (CAMK2D Produits)

Synonymes: anticorps CAMKD, anticorps CAMK1, anticorps Camk2, anticorps Camki, anticorps RATCAMKI, anticorps camk2, anticorps camkd, anticorps camkII, anticorps 2810011D23Rik, anticorps 8030469K03Rik, anticorps [d]-CaMKII, anticorps mKIAA4163, anticorps calcium/calmodulin dependent protein kinase II delta, anticorps calcium/calmodulin-dependent protein kinase II delta, anticorps calcium/calmodulin dependent protein kinase (CaM kinase) II delta S homeolog, anticorps calcium/calmodulin dependent protein kinase (CaM kinase) II delta, anticorps calcium/calmodulin-dependent protein kinase II, delta, anticorps CAMK2D, anticorps Camk2d, anticorps camk2d.S, anticorps camk2d

Sujet: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

Poids moléculaire: 56 kDa

ID gène: 817

UniProt: Q13557

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration