Ubiquilin 1 anticorps

N° du produit ABIN2856811

Cet anticorps Lapin Polyclonal détecte spécifiquement Ubiquilin 1 dans WB, IF et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour Ubiquilin 1 anticorps (ABIN2856811)

Antigène: Ubiquilin 1 (UBQLN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ubiquilin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Ubiquilin 1 anticorps

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to Ubiquilin-1 (ubiquilin 1)
Ubiquilin-1 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Ubiquilin 1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Ubiquilin 1

Antigène: Ubiquilin 1 (UBQLN1)

Autre désignation: ubiquilin 1

Sujet: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cytoplasm , Nucleus

Poids moléculaire: 63 kDa

ID gène: 29979

UniProt: Q9UMX0