CASP14 anticorps (C-Term)

N° du produit ABIN2856832

Détail du produit anti-CASP14 anticorps

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP14 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to Caspase 14 (caspase 14, apoptosis-related cysteine peptidase)
Caspase 14 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Caspase 14. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431 , PC-3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CASP14 (ABIN2856832)

Dang, Pang, Song, An, Ma: "Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes." dans: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 28-33, (2016) (PubMed).

Détails sur CASP14

Antigène: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Autre désignation: caspase 14 (CASP14 Produits)

Synonymes: anticorps CASP14, anticorps MICE, anticorps mini-ICE, anticorps caspase 14, apoptosis-related cysteine peptidase, anticorps caspase 14, anticorps caspase-14-like, anticorps caspase-14, anticorps CASP14, anticorps Casp14, anticorps LOC485601, anticorps LOC780455

Sujet: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Cellular Localization: Cytoplasm , Nucleus

Poids moléculaire: 28 kDa

ID gène: 23581

UniProt: P31944