beta 2 Adrenergic Receptor anticorps (C-Term)
Aperçu rapide pour beta 2 Adrenergic Receptor anticorps (C-Term) (ABIN2857031)
Antigène
Voir toutes beta 2 Adrenergic Receptor (ADRB2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Réactivité croisée
- Humain
-
Attributs du produit
-
Rabbit Polyclonal antibody to beta 2 Adrenergic Receptor (adrenergic, beta-2-, receptor, surface)
beta 2 Adrenergic Receptor antibody [C2C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogène
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human beta 2 Adrenergic Receptor. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Commentaires
-
Validation: Overexpression
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.31 mg/mL
-
Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
-
Autre désignation
- adrenoceptor beta 2
-
Sujet
-
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Cellular Localization: Cell membrane -
Poids moléculaire
- 46 kDa
-
ID gène
- 154
-
UniProt
- P07550
-
Pathways
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
Antigène
-