ADRA1B anticorps (C-Term)

N° du produit ABIN2857085

L’anticorps Lapin Polyclonal anti-ADRA1B a été validé pour WB. Il convient pour détecter ADRA1B dans des échantillons de Humain.

Aperçu rapide pour ADRA1B anticorps (C-Term) (ABIN2857085)

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADRA1B anticorps

Épitope: C-Term

Réactivité croisée: Souris

Attributs du produit: Rabbit polyclonal antibody to alpha 1b Adrenergic Receptor (adrenergic, alpha-1B-, receptor)
alpha 1b Adrenergic Receptor antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human alpha 1b Adrenergic Receptor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.34 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ADRA1B

Antigène: ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Autre désignation: adrenoceptor alpha 1B

Sujet: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Cellular Localization: Cell membrane

Poids moléculaire: 57 kDa

ID gène: 147

UniProt: P35368

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process