DRD3 anticorps

N° du produit ABIN285754

Cet anticorps Lapin Polyclonal détecte spécifiquement DRD3 dans WB, ELISA et IHC. Il présente une réactivité envers Rat.

Aperçu rapide pour DRD3 anticorps (ABIN285754)

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DRD3 anticorps

Specificité: This AB is 100 % conserved in Mouse and Rat, 91% in Golden hamster, 83% in Rabbit and Pig, and 75% in Human and Canine.

Réactivité croisée (Details): This rat D3R peptide sequence is 88 % conserved in mouse and 63 % with human/monkey D3R receptors (1-2). No significant sequence homology with other dopamine receptors (D1, D2, D4 or D5).

Immunogène: Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in PBS at 1 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur DRD3

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Autre désignation: Dopamine D3 Receptor

Sujet: Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity