PDGFRB anticorps (AA 1013-1025)

N° du produit ABIN285907

Cet anticorps Lapin Polyclonal détecte spécifiquement PDGFRB dans WB, IP et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour PDGFRB anticorps (AA 1013-1025) (ABIN285907)

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFRB est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Détail du produit anti-PDGFRB anticorps

Épitope: AA 1013-1025

Réactivité croisée: Souris

Purification: Protein G affinity chromatography

Immunogène: PDGF receptor beta antibody was raised in rabbit using a synthetic peptide (QPNEGDNDYIIPLA) corresponding to amino acids 1013-1025 of human PDGF receptor beta as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Frozen

Concentration: Lot specific

Buffer: Frozen in 0.1 M tris-glycine buffer, pH 7.4, with 0.11 NaCl, and 0.05 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20 °C.

Détails sur PDGFRB

Antigène: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Autre désignation: PDGF Receptor beta

Sujet: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Poids moléculaire: 190 kDa (predicted detection band MW)

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling