Perforin 1 anticorps

N° du produit ABIN285909

Cet anticorps anti-Perforin 1 Polyclonal Lapin (ABIN285909) détecte spécifiquement Perforin 1 dans WB. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour Perforin 1 anticorps (ABIN285909)

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Perforin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Perforin 1 anticorps

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): Reacts with both rat and mouse perforin. Cross-reactivity to perforin of other species has not been tested.

Purification: purified

Immunogène: Perforin antibody was raised in rabbit using E. coli-expressed rat perforin as the immunogen.

Information d'application

Indications d'application: WB: 1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitue in distilled water.

Concentration: Lot specific

Buffer: Supplied as a lyophilized Potein A purified rabbit IgG with 0.1 % NaN3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur Perforin 1

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Autre désignation: Perforin

Sujet: Perforin-1 is a protein that in humans is encoded by the PRF1 gene. Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF domain. This region shares homology with cholesterol-dependent cytolysins from Gram-positive bacteria.

Pathways: Apoptose, Caspase Cascade in Apoptosis