Resistin anticorps (Biotin)
Aperçu rapide pour Resistin anticorps (Biotin) (ABIN288463)
Antigène
Voir toutes Resistin (RETN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Immunogène
- Resistin antibody (biotin) was raised in goat using highly pure recombinant human resistinas the immunogen.
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Indications d'application
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ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in sterile PBS with 0.1 % BSA to a concentration of at least 50 µg/mL
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Resistin (RETN)
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Autre désignation
- Resistin
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Sujet
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.
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Poids moléculaire
- 20.2 kDa (predicted detection band MW)
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
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