IL1A anticorps
Aperçu rapide pour IL1A anticorps (ABIN289344)
Antigène
Voir toutes IL1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- IL1 a antibody was raised in rabbit using highly pure recombinant murine IL-1 as the immunogen.
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Indications d'application
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ELISA: 0.5-2 µg/mL, Inhibition: 0.03-0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in sterile water at a concentration of >0.2 mg/mL.
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IL1A (Interleukin 1 alpha (IL1A))
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Autre désignation
- IL1a
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Sujet
- IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.
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Poids moléculaire
- 17.7 kDa (predicted detection band MW)
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Pathways
- Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
Antigène
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