Oncostatin M anticorps

N° du produit ABIN289518

Cet anticorps anti-Oncostatin M est un anticorps Lapin Polyclonal détectant Oncostatin M dans WB, ELISA et Inhibition. Adapté pour Humain.

Aperçu rapide pour Oncostatin M anticorps (ABIN289518)

Antigène: Oncostatin M (OSM)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oncostatin M est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Détail du produit anti-Oncostatin M anticorps

Purification: Purified

Immunogène: Oncostatin M antibody was raised in rabbit using highly pure recombinant human oncostatin M as the immunogen.

Information d'application

Indications d'application: ELISA: 0.5-2 µg/mL, Inhibition: 0.1-0.175 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of > 0.2 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from 0.5 x PBS, pH 7.4.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur Oncostatin M

Antigène: Oncostatin M (OSM)

Autre désignation: Oncostatin M

Sujet: Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activate T cells, monocytes and Kaposi’s sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL6, and CNTF. Human OSM is active on Mouse cells.

Poids moléculaire: 23.9 kDa (predicted detection band MW)

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion