Mannose Receptor anticorps

N° du produit ABIN291690

Cet anticorps anti-Mannose Receptor est un anticorps Souris Monoclonal détectant Mannose Receptor dans IHC et IHC (fro). Adapté pour Humain.

Aperçu rapide pour Mannose Receptor anticorps (ABIN291690)

Antigène: Mannose Receptor (MR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mannose Receptor est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 7-450

Détail du produit anti-Mannose Receptor anticorps

Specificité: Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.

Purification: Affinity purified

Immunogène: Monocyte-derived dendritic cells.

Type of Immunogen: Cells

Isotype: IgG2a

Information d'application

Indications d'application: Approved: IHC, IHC-Fr (1:50 - 1:500)

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur Mannose Receptor

Antigène: Mannose Receptor (MR)

Autre désignation: Mannose Receptor / CD206

Sujet: Name/Gene ID: MRC1

Synonyms: MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL

ID gène: 4360